pentobarbital will lower the extent or outcome of fosamprenavir by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Watch.

pentobarbital will lower the level or result of buprenorphine by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Watch.

pentobarbital will reduce the level or outcome of theophylline by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Keep track of.

pentobarbital will minimize the level or outcome of bosentan by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Small/Importance Not known.

pentobarbital will reduce the level or result of fosphenytoin by influencing hepatic enzyme CYP2C9/ten metabolism. Use Caution/Keep track of.

Contraindicated (one)pentobarbital will decrease the extent or result of roflumilast by influencing hepatic/intestinal enzyme CYP3A4 metabolism.

pentobarbital will reduce the extent or effect of voriconazole by impacting hepatic enzyme CYP2C9/ten metabolism. Small/Importance Not known.

pentobarbital will lower the extent or impact of parecoxib by impacting hepatic enzyme CYP2C9/ten metabolism. Use Warning/Keep track of.

To attenuate the potential of overdosage or the event of dependence, limit the prescribing and dispensing of sedative-hypnotic barbiturates, to the amount demanded to the interval till the following appointment

pentobarbital will minimize the level or effect of oliceridine by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Observe. If coadministration with a CYP3A4 inducer is critical, contemplate increasing oliceridine dose until eventually steady drug effects are attained; keep track of for indications of opioid withdrawal.

Observe Intently (one)pentobarbital will lower the level or impact of fentanyl intranasal by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Observe Intently. Coadministration of fentanyl with CYP3A4 inducers may lead into a reduce in fentanyl plasma read more concentrations, lack of efficacy or, possibly, enhancement of the withdrawal syndrome within a affected person who has made physical dependence to fentanyl. Following stopping a CYP3A4 inducer, given that the effects with the inducer decrease, the fentanyl plasma focus will raise which could boost or prolong both equally the therapeutic and adverse effects.

pentobarbital will minimize the level or effect of paclitaxel protein sure by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Small/Importance Mysterious.

pentobarbital will lower the level or impact of nimodipine by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Small/Significance Unknown.

pentobarbital will minimize the extent or result of voriconazole by influencing hepatic enzyme CYP2C9/ten metabolism. Small/Importance Unfamiliar.